ANABOLIC STEROIDS AND TESTOSTERONE ENANTHATE 250

Testosterone enanthate 250, the so-called male hormone, is the most important androgen in the body. In men, most testosterone is produced in the testicles by Leydigin cells. Some testosterone enanthate 250is also produced in the adrenal cortex and in the periphery by converting androstenedione. Women have much lower testosterone levels than men. However, it also has an important effect on the female body. In women, testosterone  enanthate 250 is produced in the ovaries and adrenal cortex. Hormonal regulation of testosterone is maintained and controlled by the hypothalamus -pituitary gland axis.

Androgens have androgenic, anabolic and psychological effects on the body. Androgenic effects include penis and prostate growth, hair growth in various areas, and baldness. Anabolic effects include enlargement of the larynx, thickening of the vocal cords, lipid changes, muscle growth, fat loss, enlargement of sebaceous glands, and blood cell formation. The psychological effects of androgens include changes in libido, potency, sexual behavior, and aggression.

Anabolic steroids are synthetic derivatives of testosterone. In medicine, anabolic steroids have been used to try to achieve the anabolic effects of testosterone enanthate 250 without the virilizing side effects of androgens so that children and women can also use them. However, the attempt failed. For this reason, the term “anabolic steroid” is misleading. It is more correct to use the term “anabolic androgenic steroid”.

History of

The history of testosterone use can be traced back to 1935, when testosterone enanthate 250 was successfully isolated from bull testicles. It was fairly quickly discovered that oral testosterone enanthate cycle is hepatotoxic and has a fast half-life. Following the synthesis of testosterone, injectable propionate came onto the market, and later, in the 1950s, longer-acting enanthate . In the 1950s and 1960s, the pharmaceutical industry became increasingly interested in new androgens, and by the end of the 1980s, a huge number of anabolic steroids, over a thousand, had been developed.

Mechanism of influence

The popularity of testosterone enanthate 250 as a doping is due to its strong effect on muscle strength and mass. Testosterone also affects lipolysis , i.e., the breakdown of fat cells. Both short term and long term use of anabolic steroids results in increased cell growth due to increased protein synthesis. Testosterone-induced growth of muscle cells is due to the activation of satellite cells and the growth of muscle cell nuclei.

The number of androgen receptors is limited, and usually normal testosterone enanthate half life levels are enough for them. Therefore, muscle growth is not necessarily due to an excess of anabolic steroids. Another mechanism that explains muscle growth may be the effect of anabolic steroids on cortisol. Cortisol is a catabolic hormone and anabolic steroids can reduce its effect.

Application in medicine

According to the classification, these substances are those whose use is allowed only for the treatment of diseases confirmed by the drug control authorities. These diseases include, but are not limited to, Testosterone enanthate 250 Deficiency Syndrome (TDS), which develops due to dysfunction of the pituitary gland or testes, various types of anemia, osteoporosis and chronic protein deficiency diseases, and slow tissue healing. Testosterone is also used to treat the symptoms of the male equivalent of menopause.

Testosterone enanthate 250 is used in injectable form as a mixture of various testosterone esters.

Use as doping

The most important reason for using testosterone enanthate 250 and anabolic steroids is to improve athletic performance. The quick results and the slowdown in the development of muscle growth, of course, can certainly motivate to apply. The motivation of weightlifters is to improve athletic performance. Other motives for use include increasing workout performance, burning fat, slowing down the changes caused by aging, boosting self-confidence, and improving mood.

Anabolic steroids are often used in cycles. The course of application can last from several weeks to several years, but on average several months. There are often breaks of several months between periods of use. In the initial phase of the application, the dose of steroids is increased gradually. In the final phase, the use of steroids is gradually stopped over 1-2 weeks. The purpose of the breaks is to reduce side effects and restore the hormonal function of the body.

Side effects

Androgen receptors are present everywhere in the body, and therefore anabolic steroids affect the functioning of various internal organs. Because of this, there are a number of possible side effects. The risk of side effects increases with prolonged use of high doses.

Testosterone enanthate 250 and anabolic steroid preparations also affect the central nervous system. The areas in the brain that they affect are closely related to the centers that regulate mood. Therefore, changeable mood can be noticed.