The impact of regular intake of generic name for cialis in patients with erectile dysfunction

Generic name for cialis is a medical drug aimed at restoring erectile functions, i.e. the ability to achieve and maintain an erection. Treatment is possible due to the regulation of vascular tone.

The main active ingredient of the drug is tadalafil . It belongs to the group of enzymatic inhibitors of the PDE5 type. By the way, many medicines, which include substances of the PDE5 group, are most effective.

There are similar drugs in modern medicine, such as Viagra . However, Cialis is a more modern and effective remedy due to the modified molecules of the substances in the composition. They have a longer effect on sexual function, which may not decrease after a course of treatment.

Viagra, in turn, has only a temporary effect (several hours), and a large number of factors can affect its effectiveness. If we compare the cost, then these two drugs are in the same price category. So the price of generic name for cialis is quite justified.

American company Eli is considered the official manufacturer of best prices on cialis generic. Lilly and Company . If we talk about the manufacturer, then the organization is one of the largest not only in the US market, but throughout the world. Eli _ Lilly and Company began in the 1870s. In 2005, the company bought out all the results of the research conducted by specialists from the Icos organization and began to actively promote the product on the market.

Currently, the remedy is available at any pharmacy, so anyone can buy generic name for cialis without a special prescription.

Story

The development of the drug began in the mid-90s of the last century. Then the Icos scientists decided to conduct laboratory studies of the active substances of drugs that are designed to treat sexual dysfunctions in men.

One of the prototypes was sildenafil citrate, which was part of Viagra. The aim of the study was to find a more effective way to treat impotence.

The fact is that the effect of the world-famous Viagra lasts only for 3-5 hours, while the remedy itself is not aimed at eliminating the causes of dysfunction. Another disadvantage is slow absorption, i.e. absorption of active substances. How quickly and effectively Viagra will begin to act is influenced by additional factors, such as alcohol and fatty foods.

Therefore, scientists have worked on the composition of active substances, as a result of which generic name for cialis appeared , which can be absorbed regardless of additional negative factors.

Possible dosages

The manufacturer determines the standard dosage of the drug – 20 mg. It is not recommended to start taking Cialis generic price with a higher dosage. If there are no severe chronic diseases of the liver, kidneys, heart and other organs, then dose adjustment is not required. At the same time, the time of taking the medicine does not matter: you can use generic name for cialis during breakfast, lunch or dinner. But no more than 1 time per day.

Drug properties

The effect of the drug begins already about 15 minutes after ingestion: blood flow to the tissues of the penis is activated, due to which an erection is possible. In some cases, the effect can last up to 36 hours (but only with sexual stimulation).

The effectiveness of generic name for cialis generic cheap has been tested in clinical trials. The test also revealed the safety of the drug. The duration of the tests did not exceed six months. The number of subjects – more than 5,000 thousand, age from 20 to 87 years.

All participants in the study were initially diagnosed with erectile dysfunction of varying degrees, and some had comorbidities.

To test the drug, patients were prescribed Cialis in various doses (from 5 to 20 ml, depending on the current state of health). The subjects were divided into several groups, also depending on the current state of health.

In all cases, generic name for cialis showed a significant improvement in the state of the reproductive system, and restored erectile function. Over time, the effect of the treatment did not decrease, and remained stable.

Most of the subjects declared a normal erection within half an hour after taking a certain dose of the active substance: 10 mg – 40% of the subjects, and 20 mg – 52%.

Pharmacological action of the drug

To understand the principle of the drug, you need to understand how an erection occurs. As you know, it is possible with a rush of blood to the tissues of the penis. In the usual case, in the absence of health problems, smooth muscles relax, due to which normal blood circulation in the tissues is possible.

In turn, the nerve endings respond to the blood flow with the release of nitric oxide and endothelial cells. Nitric oxide determines how actively cyclic guanosine monophosphates ( cGMP ) interact with each other in smooth muscle tissues.

CGMP – nucleotides, or in other words – organic compounds that help relax muscles, which, in turn, contribute to greater blood flow.

How to take the drug

The indication for the use of the drug is a violation of erectile functions.

The drug is a film-coated tablet. The dose of one tablet is 5 mg. Take inside.

Contraindications

Contraindications to the use of the drug are the following factors:

• hypersensitivity, individual intolerance to the components of active substances and auxiliary elements;
• taking the drug in parallel with other drugs from the nitrate group in any form;
• severe liver failure;
• retinal diseases;
• treatment with alpha- blockers.

Side effects

Like any other drug, Cialis can cause a number of side effects. All of them were identified during clinical trials in which men aged 19 to 87 took part. On average, the presence of side effects was observed only in 3% of the subjects.

Side effects:

• Headache;
• Pain in the back and limbs:
• digestive problems;
• Pain in the muscles;
• Nasal congestion.

Symptoms may appear 12-24 hours after taking the drug, and disappear within 2 days. Muscle pains were manifested slightly, in the form of discomfort or pain in the lower back, muscles of the buttocks and thighs. May worsen when lying down.